Interferences from blood collection tube components on clinical chemistry assays
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چکیده
منابع مشابه
Interferences from blood collection tube components on clinical chemistry assays
Improper design or use of blood collection devices can adversely affect the accuracy of laboratory test results. Vascular access devices, such as catheters and needles, exert shear forces during blood flow, which creates a predisposition to cell lysis. Components from blood collection tubes, such as stoppers, lubricants, surfactants, and separator gels, can leach into specimens and/or adsorb an...
متن کاملImpact of blood collection devices on clinical chemistry assays.
Blood collection devices interact with blood to alter blood composition, serum, or plasma fractions and in some cases adversely affect laboratory tests. Vascular access devices may release coating substances and exert shear forces that lyse cells. Blood-dissolving tube additives can affect blood constituent stability and analytical systems. Blood tube stoppers, stopper lubricants, tube walls, s...
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The Clinical and Laboratory Standards Institute (CLSI) recently abandoned its recommendation for drawing a discard tube when performing a prothrombin time (PT)/international normalized ratio (INR) or an activated partial thromboplastin time (APTT). Because there is currently no evidence that a discard tube is necessary for more specialized coagulation assays, we studied the need for a discard t...
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متن کاملGraphical comparisons of interferences in clinical chemistry instrumentation.
Instrument- and analyte-specific interferences can be produced by adding known concentrations of potentially interfering substances to serum from healthy volunteers. Analytical results are expressed as a percentage of the original (unaffected) result. Graphical displays of the transformed data document the conditions under which erroneous results would be probable for specimens containing the a...
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ژورنال
عنوان ژورنال: Biochemia Medica
سال: 2014
ISSN: 1846-7482
DOI: 10.11613/bm.2014.006